RAPID AND PERSISTENT SELECTION OF THE K103N MUTATION AS A MAJORITY QUASISPECIES IN A HIV1-PATIENT EXPOSED TO EFAVIRENZ FOR THREE WEEKS: A CASE REPORT AND REVIEW OF THE LITERATURE

Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature

Abstract Introduction Selection of the K103N mutation is associated with moderately reduced in vitro fitness of HIV.Strains bearing K103N in vivo tend to persist, even in the absence of additional drug pressure, as minority quasispecies, often undetectable in genotyping resistance testing assays, performed at standard conditions.Here, we report on

read more

Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID

Background: Post-acute sequelae of COVID-19, or long COVID, is a condition characterized by persistent COVID-19 symptoms.As long COVID is defined by clinical criteria after an elapsed period, an opportunity for early intervention may aid in future prophylactic approaches; however, at present, the pathobiological mechanisms are multifactorial.By ana

read more



A comparison of approaches to art in the constitutions of the Orders of the Discalced Carmelites and Trinitarians

The reform process of the Order of the Most Holy Trinity (Trinitarians) developed under the strong influence of the Teresian Carmel, which is reflected in the dependence of the first constitutions of the Discalced Trinitarians Bio-Template Synthesis of V2O3@Carbonized Dictyophora Composites for Advanced Aqueous Zinc-Ion Batteries (1614) on the stat

read more